Recent Advances in Drug Design and Drug Discovery for Androgen- Dependent Diseases

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Recent Advances in Drug Design and Drug Discovery for Androgen-Dependent Diseases

This article summarizes the importance of different targets such as 5α-reductase, 17β-HSD, CYP17A, androgen receptor and protein kinase A for the treatment of prostate cancer and benign prostatic hyperplasia. It is a well known fact that dihydrotestosterone (DHT) is associated with the development of androgen-dependent afflictions. At the present time, several research groups are attempting to ...

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ژورنال

عنوان ژورنال: Current Medicinal Chemistry

سال: 2016

ISSN: 0929-8673

DOI: 10.2174/0929867323666160210125642